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Mohan, N. R.
- Design, Synthesis and Pharmacological Evaluation of Novel Bis Acid Amides as Antibacterial and Anti-Inflammatory Agents
Authors
1 Department of PG Studies in Chemistry, Shridevi PG Centre, Sira Road, Tumkur, Karnataka, IN
2 Department of PG Studies and Research in Chemistry, Tumkur University, Tumkur, Karnataka, IN
Source
International Journal of Innovative Research and Development, Vol 5, No 11Sp (2016), Pagination: 202-206Abstract
Opening of the five-member ring of dihydrofuran-2,5-dione with amines was used to synthesize a series of amides of4-oxo-4-(substituted) butanoic acid.4-oxo-4-(substituted) butanoic acidamine coupling using 1,1'-carbonyldiimidazole (CDI) was designed to synthesize newbis-acid amide derivatives and pharmacological activities of the compounds were evaluated. Good functional group transformations were observed upon conventional synthesis. Infrared spectroscopy (IR), 1H and 13C nuclear magnetic resonance (NMR) and liquid chromatography-mass spectrometry (LC-MS) analysis were used to establish the structures of the newly synthesized compounds. All the compounds were tested for in-vitro antibacterial and anti-inflammatory activity, some of the compounds were proven to be potent antibacterial and anti-inflammatory agents.
Keywords
Carbon-Nitrogen Bond Formation, Pharmacology, 1,1'-Carbonyldiimidazole, Antimicrobial, Anti-Inflammatory.- On Scale and Exponent Functions of a Class of Limiting Processes
Authors
1 Department of Statistics, University of Mysore, Manasagangotri, Mysore-570 006, IN
Source
Journal of the Ramanujan Mathematical Society, Vol 7, No 1 (1992), Pagination: 33-42Abstract
Suppose {Xn, n ∈ Z+) - see below for the notations used - is a sequence of random variables (rv's) such that, for every t > 0 and for ψ given by (1.1) below,
ψ(X(nt);αn;βn)->Y(t),
where Y\l) (in particular) is (assumed) nondegenerate. Then it is shown that, for some positive functions α and β on (0,∞) and for every t > 0,
Y(t)=ψ(Y(1);α(t),β(t))
Explicit expressions for a and p are derived. As an application, the (Pancheva) class of all possible limit laws for power normalized partial maxima of i.i.d rv's ("the p-max stable laws") is re-derived.